ERYTHROCYTES PHENOTYPES AND COVID-19 INFECTION
Keywords:
SARS-CoV-2, Covid-19, blood groups, rhesus factor, morbidity.Abstract
Abstract. The data of research on the prevalence of erythrocyte phenotypes of the ABO blood group system and Rh factor in patients with COVID-19 infection in Ukraine and the world are presented. Aspects of the dependence of the incidence of COVID-19 on blood type at the regional level, the compatibility of the results with other research data are discussed. A retrospective analysis of 621 cases was performed to determine the influence of blood group on the incidence of coronavirus infection. The difference between the frequency of erythrocyte phenotypes in patients and nonpatients was revealed. Among patients with COVID-19, patients with blood type A (II) had the highest proportion (p < 0.05) and a decrease in the proportion of rhesus-negative carriers (p < 0.05) was observed.
References
Атраментова Л. А., Утевская О.М. Статистические методы в биологии / Л. А. Атраментова, О. М. Утевская – Горловка: Ліхтар, 2008. – 248 с.
Зуй В. Д. Взаємозв’язок між группами крові системи АВ0, резус-фактором та білковими фракціями сироватки крові людини / В. Д. Зуй, В. С. Полетюк // Вісн. Київського ун-ту. Сер. Біол. – 1975. – № 17. – С. 36–41.
Алтухов Ю. П. Генетические процессы в популяциях /Москва: Академкнига, 2003. – 431 с.
Колодченко В. П. Розподіл комбінацій еритроцитарних антигенів крові систем АВ0 та Rh у людей різного віку / В. П. Колодченко // Пробл. Старения и долголетия. – 2012. – Т. 21, № 2. – С. 163–170.
Mazhak K. Kliniczne znaczenie biochemicznych i genetycznych badań w rozpoznawaniu alergicznych chorob ukladu oddechowego / Intern. Reviev of Alergology and Clinical immunology, V.3, №2, P.47
Чень І.Б. Розподіл населення західних областей України за групами крові у зв’язку зі злоякісними захворюваннями та екологічною ситуацією : автореф. дис. на здобуття наук. ступеня кандидата біол.наук. Спец. “Екологія” / І. Б. Чень. – Чернівці, 2006. – 19 с.
Vij S. C. Genetic influence on serum creatinine, urea and uric acid / S. C. Vij, B. B. Maitrya, S. L. Mali // Indian J. Physiol. Pharmacol. – 1978. – № 3. – P. 1853−1856.
Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020; 382:727-733.
Dong E, Du H, Gardner L. An interactive Web-based dashboard to track COVID-19 in real time. Lancet Infect Dis 2020;20:533-534.
Coronaviridae Study Group of the International Committee on Taxonomy of Viruses. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARSCoV-2. Nat Microbiol 2020;5:536-544.
Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020 February 24 (Epub ahead of print).
Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020;395:1054-1062.
Chen R, Liang W, Jiang M, et al. Risk factors of fatal outcome in hospitalized subjects with coronavirus disease 2019 from a nationwide analysis in China. Chest 2020 April 15.
Richardson S, Hirsch JS, Narasimhan M, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA 2020;323(20):2052-2059.
Levi M, Thachil J, Iba T, Levy JH. Coagulation abnormalities and thrombosis in patients with COVID-19. Lancet Haematol 2020;7(6):e438-e440
COVID-19 Host Genetics Initiative. The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic. Eur J Hum Genet 2020; 28: 715-718.
Zhao J, Yang Y, Huang H, et al. Relationship between the ABO blood group and the COVID-19 susceptibility. March 27, 2020. DOI: 10.1101/2020.03.11.20031096. (https://www.medrxiv.org/content/10.1101/2020.03.11.20031096v2. opens in new tab).
Murray GP, Post SR, Post GR. ABO blood group is a determinant of von Willebrand factor protein levels in human pulmonary endothelial cells. J Clin Pathol 2020;73: 347-349.
