TOXIC PROPERTIES OF MONOMETHYL ETHER DIPROPYLENE GLYCOL FOR MAMMALS IN DIFFERENT ROUTES OF ARRIVAL (REVIEW)
Keywords:
dipropylene glycol monomethyl ether, toxic properties.Abstract
Abstract. The review presents research and mechanisms of toxicitydipropylene glycol monomethyl ether. It has been shown that according to the parameters of acute toxicity by oral and inhalation routes of entry into the body of mammals, dipropylene glycol monomethyl ether belongs to low-toxic substances. The reagent does not irritate the skin, is not a skin sensitizer, but causes a local irritant effect of the mucous eyes in rabbits. Dipropylene glycol monomethyl ether has a depressant effect on the central nervous system after acute exposure to high concentrations and under conditions of chronic inhalation exposure. Studies in rats have shown that dipropylene glycol methyl ether does not cause reproductive toxicity and is not a carcinogen.
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