STUDYING STRESS REACTIONS IN THE BLOOD OF PATIENTS WITH COMBINED MID-FACIAL TRAUMA AND APPLICATION IN REHABILITATION OF TRANSCRANIAL ELECTRICAL STIMULATION
DOI:
https://doi.org/10.32782/3041-1394.2024-1.2Keywords:
transcranial electrical stimulation, skull-brain traumaAbstract
Purpose of the study. The aim of this research was to compare the effectiveness of transcranial electrical stimulation to normalize the regulatory functions of the CNS in the postoperative period of treatment of patients with bone injuries of the middle face. Research methods. The study was performed in 47 patients with combined mid-facial trauma, characterized by the presence of mild traumatic brain injury (concussion, brain contusion of mild severity) and severe injuries of the facial skeleton – 1, 3, 4, 7 classes according to the Yu.I. Bernadsky classification. After surgical treatment, all patients were divided into two groups. Conservative treatment according to the traditional scheme described above was used for rehabilitation of patients in the control group (22 patients). The same scheme was used for the treatment of patients of the main group (25 patients), but it was supplemented by a course of transcranial electrical stimulation, which was performed using a low-frequency electrotherapy device “Radius-01 FT”. The parameters of transcranial electrical stimulation were established according to the literature of similar studies [20; 21; 22], and were DPS = 5%, 70 Hz, 0.11 ms with a session duration of 35 minutes 1 time per day with a course of treatment of 10 days. The 7th and 14th days were chosen as the terms of observation of the effect of its influence on the body’s resistance to stress factors, while hematological studies were selected as indicators to determine the content of β-endorphins, ACTH and cortisol, and to calculate the Garkavi stress index. Scientific novelty. Studies have shown that the use of transcranial electrical stimulation helped to normalize the tone of anti-stress defense mechanisms, stimulated endodorphic structures of the brain and reduced the intensity of pain in patients with combined mid-facial trauma. Already on the 7th day, the content of stress-limiting hormones β-endorphins in the plasma of the main group patients was higher compared to that of the control (15.4 ± 1.8 pg / ml to 12.73 ± 1.6 pg / ml with g > 0.05), Conclusions. The obtained data indicate a positive therapeutic effect of transcranial electrical stimulation on the stress-limiting endogenous opiate system.
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